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Potential
Uses of Tissue Engineered SIS Wound Matrix
(Acute
Traumatic Wounds)
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Wounds
caused by acute tissue trauma are either
partial thickness where a portion of
dermis is lost or full thickness where all
dermal elements are lost.
Acute wounds can usually be readily
debrided to a viable wound bed because
infection is not likely in the first few
hours after injury.
Small partial or full thickness
wounds, which have the ability to
re-epithelialize would benefit from
application of a bioactive wound matrix as
a wound defect can be filled and matrix
components added.
The result is an improved wound
healing environment as well as a decrease
in pain as application closes the wound
covering the pain fibers.
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| Figure
6: Acute Traumatic Wound |
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Day
5 of full thickness abrasion injury to finger
being treated with OASIS®
wound dressing. Note that the first dressing
has already been incorporated.
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Figure
7:Treatment with OASIS®
wound matrix |
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Day 12: wound completely healed at 2 weeks
after placement of two OASIS®
wound dressings 5 days apart. |
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Figure
8: Acute Traumatic Wound |
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Full thickness
skin loss on the tip of the index finger,
debrided and subsequently covered with OASIS®
wound matrix. A skin graft would also close
the wound but there would be diminished skin
sensation on the tip of the index finger with
a skin graft. Closure by contraction and re-epithelialization
is preferred as long as time-to-closure is not
prolonged and the tissue defect is
corrected. |
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Figure
9: Acute Wound treated with OASIS®
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Traumatic
wound at 14 days. OASIS®
wound matrix has been applied twice, 7
days apart. Note that the initial soft tissue
defect in now filled in and the wound is re-epithelialized. |
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Figure
10: Acute Traumatic Wound healed |
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Same
wound at 3 weeks. Normal contour is present
along with normal skin sensation. |
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