Burn Prevention

OASIS^® Wound Matrix is made of a complex porcine derived biological material (submucosa) found between the mucosa and muscularis, in the wall of the porcine small intestine. The freeze dried acellular natural matrix contains the natural collagen and matrix structure, the bioactive matrix proteins found in the human dermis which orchestrate healing. The martix is biologically intact. Preliminary data from clinical trials has shown a more rapid re-epithelialization rate in both acute partial thickness wounds and the harder to heal venous ulcers.

The wound matrix, when applied to a partial thickness (burn or wound) or a full thickness wound debrided to a viable wound base, improves the healing environment. The acellular matrix rapidly incorporates migrating mesenchymal cells such as fibroblasts and macrophages, forming a dermal like tissue.

The OASIS ^®Wound Matrix contains the products produced by fibroblasts which were present prior to freeze drying. These include the collagens, glycosaminoglycans heparin, fibronectin, hyaluronic acid and growth factors which remain active.

Indications: the OASIS ® matrix dressing is indicated for a variety of acute and hard to heal wounds and burns.

How supplied: Packaged in sterile freeze dried sheets to be stored at room temperature in a clean, dry location.

OASIS APPLICATION PROTOCOL

Step One:

Clean and prepare the wound bed using standard methods so the wound is free from debris and necrotic tissue. The wound may need surgical debridement to ensure the wound edges are viable.

Step Two:

Using a clean technique cut the dry OASIS sheet to a size that is just slightly larger than the wound margins. The sheet should be large enough to cover all viable wound tissue and extend just slightly beyond the wound margins.

Step Three:

Position the cut dry OASIS sheet on the wound surface so that it overlaps all wound edges. While holding OASIS in place, gently pour sterile saline or Ringer’s solution over OASIS to rehydrate. OASIS may also be re-hydrated in a bowl of sterile saline before it is placed on the wound.

Step Four:

If the wound is larger than one sheet, use as many OASIS sheets as needed to cover the entire wound as well as slightly overlapping the wound edges.

Step Five:

Use a non-adherent secondary dressing over OASIS to keep the OASIS in place and to maintain a moist environment. Change the secondary dressing as needed. Keep OASIS moist but not too wet or macerated by varying the choice of dressing based on the top of wound and amount of exudates. DO NOT LET THE OASIS DRY OUT.

Step Six:

After each secondary dressing change, make sure OASIS is covering the wound surface. Place additional OASIS in areas not properly covered.

Step Seven:

Continue to check the wound at least once a week and place additional OASIS as needed until the wound has completely epithelialized or is closed by another means, e.g. graft flap. Remove excess fluid buildup that can cause the OASIS to float away from the wound surface.

NOTE:

During secondary dressing changes, a caramel colored gel might be seen on the wound. This is common and a result of OASIS being combined with body fluids. The gel should be rinsed away with gentle irrigation. Place additional OASIS to cover the wound if needed. Never forcibly remove OASIS from the wound bed. This could disturb budding epithelial cells on the wound edge.